Curcumin is a natural health enhancer with a long history of use in Ayurvedic (Indian) medicine for supporting a healthy inflammatory response, promoting detoxification of the body, and easing occasional minor digestive upset. By promoting healthy levels of histamine and cortisone, curcumin supports a healthy inflammation response to comfort aching joints. Curcumin herbal extract may improve angiogenesis and accumulation of extracellular matrix. Curcumin is an extract obtained from the culinary spice Turmeric. Native to tropical regions of south Asia, Turmeric is traditionally known for its anti-inflammatory properties.

Researchers at UCLA have identified a novel use for this compound in the treatment of pancreatitis. In a rat model of pancreatitis, curcumin decreased the level of several markers that are typically used to diagnose the disease including serum lipase and amylase concentrations, neutrophil accumulation and trypsin activation. Research on families immigrating from India to the United States may reflect the importance of Curcumin in the diet. It is well documented that cancer rates in India are lower than those seen in Western countries.

Curcumin is also being studied as a treatment for Alzheimer's disease and psoriasis. Curcumin, the yellow pigment of turmeric or haldi, has received attention as a promising dietary supplement for cancer prevention and treatment. This study demonstrates that curcumin nanoassemblies human hepatocellular carcinoma growth. find out more about this supplement

Curcumin may help to treat or prevent several health conditions, including high cholesterol and Curcumin cancer. It may also have antioxidant effects and may stimulate the immune system. Curcumin inhibits tumor formation induced by ben(a)pyrene(BP), and 7,12-dimethylbenz(a)antracen (DMBA) in mouse model of gastric and skin tumors, respectively [51 -53 ]. Furthermore, the administration of 4% curcumin in the diet of azoxymethane-treated mice reduced the number of colon tumors by 66% [54 ]. Curcumin restored renal function in ADR rats, as judged by the increase in GFR. The data also demonstrate that curcumin protects against ADR-induced renal injury by suppressing oxidative stress and increasing kidney glutathione content and glutathione peroxidase activity.

Curcumin, a potent antioxidant of dietary polyphenol, containing a standardized extract of Curcuma longa root (Zingiberaceae), has been reported to possess free radical scavenging, iron chelating and antiinflammatory activities. Intraperitoneal administration of 3-NP (20 mg/kg for 4 days) showed loss in body weight, declined motor function, poor retention of memory and changes in oxidative stress (lipid peroxidation, reduced glutathione and nitrite level) parameters in brain. Curcumin sulfate and curcumin glucuronide were identified in the tissue of these patients. Trace levels of curcumin were found in the peripheral circulation. Curcumin treatment significantly and dose dependently improved this increase in nitrite levels both in serum and tissue (Table- 2 ). However, CMN (15 mg/kg) per se had no effect on serum nitrite levels.

Curcumin also inhibited VEGFR2-positive circulating endothelial cells. Treatment of LNCaP xenografted mice with TRAIL alone had no effect on tumor growth, apoptosis, metastasis and angiogenesis. Curcumin is almost completely insoluble in water or in oils, but is soluble in alcohols. Accordingly, a method for treating inflammation in a mammal comprising administering curcumin in a solution containing at least one alcohol to a mammal to detectably inhibit the activity of phosphorylase kinase in the blood of the mammal or in a tissue of the mammal. Curcumin is an antioxidant extract from the spice turmeric that produces a wide range of health benefits. Recently, many studies on health benefits associated with curcumin have been reported.

This is not medical advice, diagnosis or treatment. You should consult your doctor if you have questions regarding any medical condition, before starting any new treatment, and before stopping any treatment that has been prescribed for you.